Ficolin-2 and ficolin-3 in women with malignant and benign ovarian tumours
نویسندگان
چکیده
منابع مشابه
Human L-Ficolin (Ficolin-2) and Its Clinical Significance
Human L-ficolin (P35, ficolin-2) is synthesised in the liver and secreted into the bloodstream where it is one of the major pattern recognition molecules of plasma/serum. Like other ficolins, it consists of a collagen-like tail region linked to a fibrinogen-related globular head; a basic triplet subunit arises via a collagen-like triple helix, and this then forms higher multimers (typically a 1...
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In the present study we performed comparative determination of the blood levels of L-ficolin and H-ficolin, opsonins and the initial components of the complement lectin pathway, in patients with Familial Mediterranean fever (FMF) in attack and attack-free periods and healthy subjects. In addition, in all study subjects serum levels of IL-1b and and total leukocyte count (TLC) were determined. F...
متن کاملEvaluation of Ficolin-3 (FCN3) 1637delC (rs28357092) Frameshift Mutation in Iranian Type 2 Diabetic Subjects
Background and Aims: Ficolins are proteins that bind to carbohydrates, act as opsonins and play an important role in innate immunity. Polymorphism in ficolin-3 gene (FCN3) can lead to complement deficiency and increase the risk of some disorders such as diabetes. The aim of this study was to investigate the frequency of FCN3+1637delC as a single nucleotide polymorphism in this gene in healthy a...
متن کاملComparison of clinical presentation of benign and malignant ovarian tumours.
OBJECTIVE To compare clinical presentation of benign and malignant ovarian tumours and to enlist and identify symptoms that could lead to early diagnosis of ovarian carcinoma METHODS It was a consecutive case series study. All patients who on abdominal or bimanual examination and abdominal U/S were found to have ovarian cyst or tumour, and later underwent laparotomy were included. RESULTS T...
متن کاملFicolin‐3/adiponectin ratio for the prediction of gestational diabetes mellitus in pregnant women
AIMS/INTRODUCTION To establish that the ficolin-3/adiponectin ratio is a predictor for gestational diabetes mellitus (GDM) and is eligible for screening tests for GDM. MATERIALS AND METHODS A prospective cohort study of 86 pregnant women who developed GDM and 273 normal glucose tolerance participants was carried out. Maternal serum ficolin-3, adiponectin levels were investigated at 16-18 week...
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ژورنال
عنوان ژورنال: Cancer Immunology, Immunotherapy
سال: 2013
ISSN: 0340-7004,1432-0851
DOI: 10.1007/s00262-013-1445-3